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Soluble Urokinase-Type Plasminogen Activator Receptor Levels in Patients With Schizophrenia

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A few more after a close peep at the screen, stating they have to catch the last bus. The etiology of schizophrenia remains largely unknown but alterations in the immune system may be involved.

In addition to the psychiatric symptoms, schizophrenia is also associated with up to 20 years reduction in life span. Soluble urokinase-type plasminogen activator BBirkerod suPAR is a protein that can be measured in blood samples and reflects the levels of inflammatory activity.

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In total we included subjects, cases with schizophrenia The mean suPAR values were 4. Patients with schizophrenia had significantly higher suPAR levels than healthy controls. Schizophrenia affects approximately 0. With these hard figures, it becomes evident that the underrecognition and undertreatment of somatic diseases in patients with schizophrenia are a significant health care problem.

The etiology of schizophrenia is largely genetic with estimates of heritability approaching 0. Approximately one-third of schizophrenia patients display an overt immunological abnormality. In addition to these findings, add-on treatment with nonsteroidal antiinflammatory drugs NSAID such as celecoxib and aspirin, has in recent, Birkerod sex models blinded studies been found to reduce the positive symptoms of schizophrenia.

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