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Soluble Urokinase-Type Plasminogen Activator Receptor Levels in Patients With Schizophrenia
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In addition to the psychiatric symptoms, schizophrenia is also associated with up to 20 years reduction in life span. Soluble urokinase-type plasminogen activator BBirkerod suPAR is a protein that can be measured in blood samples and reflects the levels of inflammatory activity.
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In total we included subjects, cases with schizophrenia The mean suPAR values were 4. Patients with schizophrenia had significantly higher suPAR levels than healthy controls. Schizophrenia affects approximately 0. With these hard figures, it becomes evident that the underrecognition and undertreatment of somatic diseases in patients with schizophrenia are a significant health care problem.
The etiology of schizophrenia is largely genetic with estimates of heritability approaching 0. Approximately one-third of schizophrenia patients display an overt immunological abnormality. In addition to these findings, add-on treatment with nonsteroidal antiinflammatory drugs NSAID such as celecoxib and aspirin, has in recent, Birkerod sex models blinded studies been found to reduce the positive symptoms of schizophrenia.
Although the exact mechanisms or involvement of the immune system in schizophrenia remains largely unknown, it may be a part of a Shady lady Lillerod grade inflammation LGI process. ❶Abstract Background: For now though, we have to abide by them and accept their advantages, and at the same time acknowledge they are only in our heads.
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