Vienna, 24 June The increasingly popular trend for fertility clinics to freeze all IVF embryos for later transfer has been shown in a large multicentre randomised trial to offer no improvement in delivery rates over traditional 'fresh' embryo transfers. So I think it can now plausibly be said that there is no indication for a general freeze-all strategy in women with regular menstrual cycles who are not at immediate risk of Ronne swinger in IVF.
Behind the study lies an increasingly adopted strategy in assisted Massage by bobbie Greve to freeze all embryos generated in a first cycle and transfer them after thawing in a later cycle rather than as fresh embryos in the initial cycle.
Some recent reports from registries in Japan and USA have suggested that there are now more frozen embryo transfers in IVF than fresh, with numbers still growing and many clinics claiming that outcomes can be improved with a freeze-all approach.
However, despite the enthusiasm of clinics, most study results investigating the freeze-all vs fresh controversy have been inconsistent in their results. This study, which aimed to test the claim of improved outcome in a general IVF patient population, was a large randomised trial involving IVF patients at eight clinics Vaerlse Denmark, Sweden and Spain and powered to provide a robust result.
The patients were randomly assigned to test the two different treatment approaches, both of them with single blastocyst transfer: Results showed that the ongoing pregnancy per randomised patient after the first single blastocyst transfer was similar in the two groups: Live birth rates were also comparable. This latter component of safety was an additional secondary endpoint to the study.
In the freeze-all cycles ovulation of the mature eggs was triggered with a reproductive hormone-suppressing drug known as a GnRH agonist; in Single lady Vaerlose conventional fresh transfer group ovulation was triggered traditionally with hCG.
And in this part of the study there was an apparent patient benefit from the freeze-all Singlr in terms of patient safety. Twenty-five of the patients in the fresh transfer group were judged at risk of ovarian hyperstimulation syndrome OHSS towards the end of their treatment cycle and, to remove the risk, they were switched to the freeze-all group.
Esbjerg full sexy, there were no signs of OHSS in the freeze-all group. The 25 patients judged at high risk of OHSS in the fresh transfer group were swopped from the fresh to How to meet women in Horsholm freeze-all group as a safety measure and according to trial protocol.
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